BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P61586   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-related GTP-binding protein RhoC/Transforming protein RhoA


(Homo sapiens (Human))		BDBM50481337
PNG
(CHEMBL594911)
Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)NOCC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C17H11ClF6N2O3/c18-12-1-3-13(4-2-12)25-14(27)8-29-26-15(28)9-5-10(16(19,20)21)7-11(6-9)17(22,23)24/h1-7H,8H2,(H,25,27)(H,26,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



University of Michigan Medical School

Curated by ChEMBL


Assay Description
Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells by serum response factor-luciferase reporter gene assay

Bioorg Med Chem Lett 20: 665-72 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.056
BindingDB Entry DOI: 10.7270/Q29S1TTD
More data for this
Ligand-Target Pair