Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1317 (3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1969 ((Alkylamino)piperidine BHAP Analog 25 | 1-[[5-[[(4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1956 ((Alkylamino)piperidine BHAP Analog 12 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1954 ((Alkylamino)piperidine BHAP Analog 10 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1967 ((Alkylamino)piperidine BHAP Analog 23 | 1-[[5-[[(4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1957 ((Alkylamino)piperidine BHAP Analog 13 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1962 ((Alkylamino)piperidine BHAP Analog 18 | N-{2-[(4-{...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1966 ((Alkylamino)piperidine BHAP Analog 22 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1963 ((Alkylamino)piperidine BHAP Analog 19 | N-{2-[(4-{...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2659 ((Alkylamino)piperidine BHAP Analog 27 | 1-[[5-[[(4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1950 ((Alkylamino)piperidine BHAP Analog 6 | {2-[(4-{met...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2661 ((Alkylamino)piperidine BHAP Analog 29 | 4-methyl-N...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1946 ((Alkylamino)piperidine BHAP analog 2 | 2-{2-[2-({2...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1968 ((Alkylamino)piperidine BHAP Analog 24 | 1-[[5-[[(4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1959 (1-[(5-Methanesulfonamidoindol-2-yl)carbonyl]-4-[N-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2312 (1,5-Diphenyl-3-methyl-4-ethylpyrazole | 1,5-Diphen...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | 8.3 | 28 |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 43: 1034-40 (2000) Article DOI: 10.1021/jm990383f BindingDB Entry DOI: 10.7270/Q2HD7SVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1964 ((Alkylamino)piperidine BHAP Analog 20 | N-{2-[(4-{...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1961 ((Alkylamino)piperidine BHAP Analog 17 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2665 ((Alkylamino)piperidine BHAP Analog 33 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1970 ((Alkylamino)piperidine BHAP Analog 26 | 1-[[5-[[(4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1949 ((Alkylamino)piperidine BHAP Analog 5 | 2-N-cyclopr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2314 (1,5-Diphenyl-3-(2-hydroxyethyl)-4-ethylpyrazole | ...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | 8.3 | 28 |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 43: 1034-40 (2000) Article DOI: 10.1021/jm990383f BindingDB Entry DOI: 10.7270/Q2HD7SVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1958 ((Alkylamino)piperidine BHAP Analog 14 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1945 ((Alkylamino)piperidine BHAP Analog 1 | 2-N-[1-(1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2667 ((Alkylamino)piperidine BHAP Analog 35 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2311 (1,5-Diphenyl-3-methylpyrazole (DPP) analogue | 2-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | 8.3 | 28 |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 43: 1034-40 (2000) Article DOI: 10.1021/jm990383f BindingDB Entry DOI: 10.7270/Q2HD7SVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2660 ((Alkylamino)piperidine BHAP Analog 28 | 1-[[5-[[(4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1955 ((Alkylamino)piperidine BHAP Analog 11 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1960 ((Alkylamino)piperidine BHAP Analog 16 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1951 ((Alkylamino)piperidine BHAP Analog 7 | 1-[(5-Metha...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1947 ((Alkylamino)piperidine BHAP Analog 3 | CHEMBL12433...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2666 ((Alkylamino)piperidine BHAP Analog 34 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2313 (1,5-Diphenyl-3-methyl-4-propargylpyrazole | 1,5-Di...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | 8.3 | 28 |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 43: 1034-40 (2000) Article DOI: 10.1021/jm990383f BindingDB Entry DOI: 10.7270/Q2HD7SVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2663 ((Alkylamino)piperidine BHAP Analog 31 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2664 ((Alkylamino)piperidine BHAP Analog 32 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1965 ((Alkylamino)piperidine BHAP Analog 21 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1952 ((Alkylamino)piperidine BHAP Analog 8 | 1-[[5-[(Met...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM2662 ((Alkylamino)piperidine BHAP Analog 30 | 1-[(5-Meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1953 ((Alkylamino)piperidine BHAP Analog 9 | 1-[(5-Metha...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1944 (BHAP deriv. | CHEMBL593 | DELAVIRDINE MESYLATE | D...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1) | BDBM1437 (5-methoxyindole-2-carboxylic acid [N -[3-(aminoeth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 39: 3769-89 (1996) Article DOI: 10.1021/jm960158n BindingDB Entry DOI: 10.7270/Q2XK8CQV | |||||||||||
More data for this Ligand-Target Pair |