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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 209227   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 1


(Mus musculus (Mouse))		BDBM209227
PNG
(US9266877, 173)
Show SMILES Cc1c(cnn1CC1(CCCCCC1)OCC1COCCO1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1
Show InChI InChI=1S/C40H44N6O6S/c1-26-31(21-41-46(26)25-40(16-6-2-3-7-17-40)52-24-28-23-50-19-20-51-28)29-13-14-35(43-36(29)38(48)49)45-18-15-27-9-8-10-30(32(27)22-45)37(47)44-39-42-33-11-4-5-12-34(33)53-39/h4-5,8-14,21,28H,2-3,6-7,15-20,22-25H2,1H3,(H,48,49)(H,42,44,47)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.100n/an/an/an/a



ABBVIE INC.

US Patent


Assay Description
The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...

US Patent US9266877 (2016)


BindingDB Entry DOI: 10.7270/Q2H41Q7V
More data for this
Ligand-Target Pair