Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasma kallikrein (Homo sapiens (Human)) | BDBM283493 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
LIFESCI PHARMACEUTICALS, INC. US Patent | Assay Description The test compounds at various concentrations, also prepared by serial dilutions as described above, are added to the test wells. The volume of test c... | US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM283493 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
ATTUNE PHARMACEUTICALS, INC. US Patent | Assay Description Materials:Plasma kallikrein inhibitor C1NH (Athens Research & Technology, Cat #16-16-031509); Ellagic acid (Sigma, E2250); Substrate Z-FR-2-AMC (GL B... | US Patent US11021463 (2021) BindingDB Entry DOI: 10.7270/Q21R6TN7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM283493 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
ENSCMu | Assay Description Human plasma is thawed on ice and centrifuged for 15 min at 4° C. to remove platelets. A 1 mM stock solution of ellagic acid is diluted to 8 μM ... | Bioorg Med Chem 14: 7241-57 (2006) BindingDB Entry DOI: 10.7270/Q2J968P7 | |||||||||||
More data for this Ligand-Target Pair |