Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...) | BDBM29589 (Faridak | LBH-589 | LBH-589B | Panobinostat | US10...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL | Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as... | J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 6 (Homo sapiens (Human)) | BDBM29589 (Faridak | LBH-589 | LBH-589B | Panobinostat | US10...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 151 | n/a | n/a | n/a | n/a |
West China Hospital of Sichuan University Curated by ChEMBL | Assay Description Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assay | J Med Chem 59: 5488-504 (2016) Article DOI: 10.1021/acs.jmedchem.6b00579 BindingDB Entry DOI: 10.7270/Q2T155K0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
