Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM30418 (BMCL185002 Compound 3a | BMCL19451 Compound 2 | py...) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <10 | n/a | 12 | n/a | n/a | 7.5 | 28 |
Anadys Pharmaceuticals | Assay Description Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v... | Bioorg Med Chem Lett 18: 3616-21 (2008) Article DOI: 10.1016/j.bmcl.2008.04.066 BindingDB Entry DOI: 10.7270/Q26D5R9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM30418 (BMCL185002 Compound 3a | BMCL19451 Compound 2 | py...) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <10 | n/a | 12 | n/a | n/a | 7.5 | 28 |
Anadys Pharmaceuticals | Assay Description Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v... | Bioorg Med Chem Lett 19: 451-8 (2009) Article DOI: 10.1016/j.bmcl.2008.11.048 BindingDB Entry DOI: 10.7270/Q2JM27Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM30418 (BMCL185002 Compound 3a | BMCL19451 Compound 2 | py...) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <10 | n/a | 12 | n/a | n/a | 7.5 | 28 |
Anadys Pharmaceuticals | Assay Description Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v... | Bioorg Med Chem Lett 18: 5002-5 (2008) Article DOI: 10.1016/j.bmcl.2008.08.017 BindingDB Entry DOI: 10.7270/Q2XW4H5X | |||||||||||
More data for this Ligand-Target Pair |