BindingDB PrimarySearch

Found 6 hits of ec50 for monomerid = 31068
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (Homo sapiens (Human))	BDBM31068 (2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...) Show SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	749	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q24B35DW
TBA					More data for this Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (Homo sapiens (Human))	BDBM31068 (2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...) Show SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	749	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...				ACS Med Chem Lett 8: 407-412 (2017) Article DOI: 10.1021/acsmedchemlett.6b00489 BindingDB Entry DOI: 10.7270/Q29Z9745
Peking University Curated by ChEMBL					More data for this Ligand-Target Pair
General amino acid permease AGP1 (Saccharomyces cerevisiae S288c)	BDBM31068 (2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...) Show SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1cccs1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	872	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q29885GJ
NMMLSC Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (Homo sapiens (Human))	BDBM31068 (2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...) Show SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q24B35DW
TBA					More data for this Ligand-Target Pair
Vacuolar aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM31068 (2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...) Show SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1cccs1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21R6P02
NMMLSC Curated by PubChem BioAssay					More data for this Ligand-Target Pair
60S ribosomal protein L19-A (Saccharomyces cerevisiae)	BDBM31068 (2-(methylsulfonyl)-4-thien-2-yl-6-(trifluoromethyl...) Show SMILES CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2JQ0ZGP
NMMLSC Curated by PubChem BioAssay					More data for this Ligand-Target Pair