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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 50000540   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50000540
PNG
(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Show SMILES NC1=NN(CC1)c1cccc(c1)C(F)(F)F |t:1|
Show InChI InChI=1S/C10H10F3N3/c11-10(12,13)7-2-1-3-8(6-7)16-5-4-9(14)15-16/h1-3,6H,4-5H2,(H2,14,15)
PDB
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CHEMBL
MCE
PC cid
PC sid
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Similars

PubMed
n/an/an/an/a 6.80E+3n/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.


J Med Chem 35: 3180-3 (1992)


BindingDB Entry DOI: 10.7270/Q2542P68
More data for this
Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))
BDBM50000540
PNG
(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Show SMILES NC1=NN(CC1)c1cccc(c1)C(F)(F)F |t:1|
Show InChI InChI=1S/C10H10F3N3/c11-10(12,13)7-2-1-3-8(6-7)16-5-4-9(14)15-16/h1-3,6H,4-5H2,(H2,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
MCE
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/an/an/a 1.30E+5n/an/an/an/a



ICI Pharma

Curated by ChEMBL


Assay Description
Ex vivo inhibition of LTB4 production was measured in dog blood


J Med Chem 34: 1028-36 (1991)


BindingDB Entry DOI: 10.7270/Q28G8MXH
More data for this
Ligand-Target Pair