Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
University of Wisconsin-La Crosse Curated by ChEMBL | Assay Description Agonist activity at rat 5HT2A receptor expressed in mouse NIH3T3 cells assessed as stimulation of inositol phosphate accumulation | Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Serotonin 5-HT2A receptor-mediated intracellular calcium [Ca2+] mobilization in rat A7r5 cells | J Med Chem 47: 6034-41 (2004) Article DOI: 10.1021/jm040082s BindingDB Entry DOI: 10.7270/Q2R78DQ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 72 | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 72 | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Tested for its ability to activate phospholipase C by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptor | J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1 | |||||||||||
More data for this Ligand-Target Pair |