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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50017370   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))		BDBM50017370
PNG
(CHEMBL3288289)
Show SMILES NCCCC[C@H](NC(=O)[C@@H](Cc1cc2ccccc2s1)NC(=O)N1CCC(CC1)N1Cc2ccccc2NC1=O)C(=O)N1CCN(CC1)c1ccncc1 |r|
Show InChI InChI=1S/C40H49N9O4S/c41-16-6-5-10-34(38(51)47-23-21-46(22-24-47)30-12-17-42-18-13-30)43-37(50)35(26-32-25-28-7-2-4-11-36(28)54-32)45-39(52)48-19-14-31(15-20-48)49-27-29-8-1-3-9-33(29)44-40(49)53/h1-4,7-9,11-13,17-18,25,31,34-35H,5-6,10,14-16,19-24,26-27,41H2,(H,43,50)(H,44,53)(H,45,52)/t34-,35+/m0/s1
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Article
PubMed
n/an/an/an/a 96n/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...

Bioorg Med Chem Lett 24: 2744-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.033
BindingDB Entry DOI: 10.7270/Q2Q241S2
More data for this
Ligand-Target Pair