Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type/Kappa-type/Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of radiolabeled dihydromorphine from opioid receptor in rat brain homogenates | J Med Chem 22: 889-90 (1979) Article DOI: 10.1021/jm00193a028 BindingDB Entry DOI: 10.7270/Q2QZ2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS binding | Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W | |||||||||||
More data for this Ligand-Target Pair |