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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50027843   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM50027843
PNG
(CHEMBL3338685)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r|
Show InChI InChI=1S/C80H132N16O18/c1-13-14-15-16-17-18-19-20-21-22-23-24-25-30-63(102)92-64(47(6)7)75(110)95-67(52(12)99)78(113)91-61(42-46(4)5)79(114)96-40-27-29-62(96)74(109)88-58(41-45(2)3)71(106)86-48(8)69(104)85-49(9)70(105)93-65(50(10)97)76(111)90-60(44-54-33-37-56(101)38-34-54)73(108)94-66(51(11)98)77(112)89-59(43-53-31-35-55(100)36-32-53)72(107)87-57(68(81)103)28-26-39-84-80(82)83/h31-38,45-52,57-62,64-67,97-101H,13-30,39-44H2,1-12H3,(H2,81,103)(H,85,104)(H,86,106)(H,87,107)(H,88,109)(H,89,112)(H,90,111)(H,91,113)(H,92,102)(H,93,105)(H,94,108)(H,95,110)(H4,82,83,84)/t48-,49-,50+,51+,52+,57-,58-,59-,60-,61-,62-,64-,65-,66-,67-/m0/s1
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Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Agonist activity at APJ receptor in HEK293 cells assessed as inhibition of forskolin-induced cAMP level incubated for 5 mins prior to forskolin chall...

Bioorg Med Chem Lett 24: 4871-5 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.045
BindingDB Entry DOI: 10.7270/Q2D50PH2
More data for this
Ligand-Target Pair