Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50054654 (CHEMBL4068839) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
High Magnetic Field Laboratory Curated by ChEMBL | Assay Description Inhibition of wild-type EGFR (unknown origin) autophosphorylation at Y1068 expressed in mouse BAF3 cells after 4 hrs by Western blot analysis | J Med Chem 60: 2944-2962 (2017) Article DOI: 10.1021/acs.jmedchem.6b01907 BindingDB Entry DOI: 10.7270/Q2WQ0680 | |||||||||||
More data for this Ligand-Target Pair |