Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-arachidonyl glycine receptor (Homo sapiens (Human)) | BDBM50056486 (((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic a...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Agonist activity at recombinant full length human GPR18 expressed in CHO cells assessed as forskolin-stimulated cAMP accumulation after 10 mins by en... | Eur J Med Chem 155: 381-397 (2018) Article DOI: 10.1016/j.ejmech.2018.05.050 BindingDB Entry DOI: 10.7270/Q22F7R1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-arachidonyl glycine receptor (Homo sapiens (Human)) | BDBM50056486 (((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic a...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Agonist activity at recombinant human GPR18 expressed in HEK293 cells assessed as induction of p44/42 MAPK phosphorylation after 5 mins by Western bl... | Eur J Med Chem 155: 381-397 (2018) Article DOI: 10.1016/j.ejmech.2018.05.050 BindingDB Entry DOI: 10.7270/Q22F7R1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-arachidonyl glycine receptor (Homo sapiens (Human)) | BDBM50056486 (((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic a...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by b... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00208 BindingDB Entry DOI: 10.7270/Q2PZ5DJH | |||||||||||
More data for this Ligand-Target Pair |