Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50084437 (Batefenterol | GSK961081 | GSK961081A | TD-5959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.251 | n/a | n/a | n/a | n/a |
School of Pharmaceutical Sciences & The Fifth Affiliated Hospital Curated by ChEMBL | Assay Description Agonist activity at human beta2 adrenoceptor | J Med Chem 62: 5944-5978 (2019) Article DOI: 10.1021/acs.jmedchem.8b01520 BindingDB Entry DOI: 10.7270/Q2GT5RNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50084437 (Batefenterol | GSK961081 | GSK961081A | TD-5959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.251 | n/a | n/a | n/a | n/a |
Theravance Biopharma, Inc. Curated by ChEMBL | Assay Description Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as cAMP accumulation using [125I]cAMP by scintillation countin... | J Med Chem 58: 2609-22 (2015) Article DOI: 10.1021/jm501915g BindingDB Entry DOI: 10.7270/Q2N29ZNQ | |||||||||||
More data for this Ligand-Target Pair |