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Compile Data Set for Download or QSAR

Found 3 hits of ec50 for monomerid = 50161087   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Homo sapiens (Human))
BDBM50161087
PNG
(9,11-Diiodo-1,2,3,4,5,6-hexahydro-1,5-methano-pyri...)
Show SMILES Ic1cc(I)c(=O)n2CC3CNCC(C3)c12 |THB:1:15:14:11.12.10|
Show InChI InChI=1S/C11H12I2N2O/c12-8-2-9(13)11(16)15-5-6-1-7(10(8)15)4-14-3-6/h2,6-7,14H,1,3-5H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 42n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Change in membrane potential in K-177 cells expressing acetylcholine central neuronal receptor alpha4-beta2 subunits


Bioorg Med Chem Lett 15: 1221-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.073
BindingDB Entry DOI: 10.7270/Q2DJ5GVR
More data for this
Ligand-Target Pair
Acetylcholine receptor protein alpha chain/beta chain/delta chain /gamma chain


(Homo sapiens (Human))
BDBM50161087
PNG
(9,11-Diiodo-1,2,3,4,5,6-hexahydro-1,5-methano-pyri...)
Show SMILES Ic1cc(I)c(=O)n2CC3CNCC(C3)c12 |THB:1:15:14:11.12.10|
Show InChI InChI=1S/C11H12I2N2O/c12-8-2-9(13)11(16)15-5-6-1-7(10(8)15)4-14-3-6/h2,6-7,14H,1,3-5H2
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>100n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptors


Bioorg Med Chem Lett 15: 1221-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.073
BindingDB Entry DOI: 10.7270/Q2DJ5GVR
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit


(Rattus norvegicus (Rat))
BDBM50161087
PNG
(9,11-Diiodo-1,2,3,4,5,6-hexahydro-1,5-methano-pyri...)
Show SMILES Ic1cc(I)c(=O)n2CC3CNCC(C3)c12 |THB:1:15:14:11.12.10|
Show InChI InChI=1S/C11H12I2N2O/c12-8-2-9(13)11(16)15-5-6-1-7(10(8)15)4-14-3-6/h2,6-7,14H,1,3-5H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Effective concentration in KXalpha-3-beta-4R2 cells expressing rat nicotinic acetylcholine receptor alpha3-beta4 subunits


Bioorg Med Chem Lett 15: 1221-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.073
BindingDB Entry DOI: 10.7270/Q2DJ5GVR
More data for this
Ligand-Target Pair