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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50380301   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))		BDBM50380301
PNG
(CHEMBL2017455)
Show SMILES Clc1ccc(cc1)-c1nc(cs1)C(=O)Nc1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C20H19ClN4OS/c21-15-3-1-14(2-4-15)20-24-18(13-27-20)19(26)23-16-5-7-17(8-6-16)25-11-9-22-10-12-25/h1-8,13,22H,9-12H2,(H,23,26)
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MMDB

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Article
PubMed
n/an/an/an/a 900n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measur...

ACS Med Chem Lett 2: 632-637 (2011)


Article DOI: 10.1021/ml200113y
BindingDB Entry DOI: 10.7270/Q2J967CS
More data for this
Ligand-Target Pair