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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50380343   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))		BDBM50380343
PNG
(CHEMBL2017806)
Show SMILES COc1ccccc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(c1)C(F)(F)F
Show InChI InChI=1S/C22H17F3N2O3/c1-30-19-10-6-5-9-17(19)20(28)27-21(29)26-15-11-12-16(14-7-3-2-4-8-14)18(13-15)22(23,24)25/h2-13H,1H3,(H2,26,27,28,29)
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Article
PubMed
n/an/an/an/a 68n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 expressed in U2OS cells coexpressing eGFP assessed as receptor internalisation after 1 hr by microscopic analysis

ACS Med Chem Lett 2: 752-757 (2011)


Article DOI: 10.1021/ml2001399
BindingDB Entry DOI: 10.7270/Q21837G0
More data for this
Ligand-Target Pair