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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 50435190   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine Aminopeptidase Type 1 (MetAP1)


(Homo sapiens (Human))
BDBM50435190
PNG
(CHEMBL2392926)
Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc(cc2)C#N)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r|
Show InChI InChI=1S/C29H28Cl2N6/c1-20-27(31)29(37-28(36-20)25-15-14-24(30)18-34-25)35-19-26(23-8-3-2-4-9-23)33-16-6-5-7-21-10-12-22(17-32)13-11-21/h2-4,8-15,18,26,33H,5-7,16,19H2,1H3,(H,35,36,37)/t26-/m0/s1
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 520n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...


Bioorg Med Chem 21: 2600-17 (2013)


Article DOI: 10.1016/j.bmc.2013.02.023
BindingDB Entry DOI: 10.7270/Q290256X
More data for this
Ligand-Target Pair
Microtubule-associated protein 2


(Homo sapiens (Human))
BDBM50435190
PNG
(CHEMBL2392926)
Show SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc(cc2)C#N)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r|
Show InChI InChI=1S/C29H28Cl2N6/c1-20-27(31)29(37-28(36-20)25-15-14-24(30)18-34-25)35-19-26(23-8-3-2-4-9-23)33-16-6-5-7-21-10-12-22(17-32)13-11-21/h2-4,8-15,18,26,33H,5-7,16,19H2,1H3,(H,35,36,37)/t26-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.60E+4n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...


Bioorg Med Chem 21: 2600-17 (2013)


Article DOI: 10.1016/j.bmc.2013.02.023
BindingDB Entry DOI: 10.7270/Q290256X
More data for this
Ligand-Target Pair