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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neurotensin receptor type 1 (Homo sapiens (Human)) | BDBM50440737 (CHEMBL2431120) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Agonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as potentiation of NT(8-13) peptide-induced change in intracellular Ca2+ l... | Bioorg Med Chem Lett 24: 3974-8 (2014) Article DOI: 10.1016/j.bmcl.2014.06.033 BindingDB Entry DOI: 10.7270/Q2ZP47RG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neurotensin receptor type 1 (Homo sapiens (Human)) | BDBM50440737 (CHEMBL2431120) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Agonist activity at NTR1 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin by GFP reporter gene assay | ACS Med Chem Lett 4: 846-851 (2013) Article DOI: 10.1021/ml400176n BindingDB Entry DOI: 10.7270/Q2959JZQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neurotensin receptor type 1 (Homo sapiens (Human)) | BDBM50440737 (CHEMBL2431120) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.87E+3 | n/a | n/a | n/a | n/a |
Sanford Burnham Prebys Medical Discovery Institute Curated by ChEMBL | Assay Description Allosteric modulation of human GFP-fused PK-tagged Gq-coupled NTR1 expressed in CHOK1 cells assessed as induction of NT (8 to 13) peptide-mediated be... | J Med Chem 62: 8357-8363 (2019) Article DOI: 10.1021/acs.jmedchem.9b00340 BindingDB Entry DOI: 10.7270/Q2HQ438V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neurotensin receptor type 1 (Homo sapiens (Human)) | BDBM50440737 (CHEMBL2431120) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.41E+3 | n/a | n/a | n/a | n/a |
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Agonist activity at NTR1 (unknown origin) expressed in CHOK1 cells by beta-arrestin assay | ACS Med Chem Lett 4: 846-851 (2013) Article DOI: 10.1021/ml400176n BindingDB Entry DOI: 10.7270/Q2959JZQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| G-protein coupled receptor 35 (Homo sapiens (Human)) | BDBM50440737 (CHEMBL2431120) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a |
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Agonist activity at GPR35 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin by GFP reporter gene assay | ACS Med Chem Lett 4: 846-851 (2013) Article DOI: 10.1021/ml400176n BindingDB Entry DOI: 10.7270/Q2959JZQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neurotensin receptor type 1 (Homo sapiens (Human)) | BDBM50440737 (CHEMBL2431120) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a |
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Agonist activity at NTR1 (unknown origin) expressed in CHO cells assessed as stimulation of calcium flux | ACS Med Chem Lett 4: 846-851 (2013) Article DOI: 10.1021/ml400176n BindingDB Entry DOI: 10.7270/Q2959JZQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
