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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50509586   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase SMYD3


(Homo sapiens (Human))		BDBM50509586
PNG
(CHEMBL4536672)
Show SMILES O=C(NC1CCN(CC1)S(=O)(=O)c1ccc(CN2CCCC2)cc1)c1cc(on1)C1CC1
Show InChI InChI=1S/C23H30N4O4S/c28-23(21-15-22(31-25-21)18-5-6-18)24-19-9-13-27(14-10-19)32(29,30)20-7-3-17(4-8-20)16-26-11-1-2-12-26/h3-4,7-8,15,18-19H,1-2,5-6,9-14,16H2,(H,24,28)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 373n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of recombinant SMYD3 (unknown origin) transfected in human HEK293 cells assessed as reduction in MEKK2 methylation incubated for 24 hrs by...

ACS Med Chem Lett 11: 133-140 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00493
BindingDB Entry DOI: 10.7270/Q2W66Q2M
More data for this
Ligand-Target Pair