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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50538579   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 7


(Homo sapiens (Human))		BDBM50538579
PNG
(CHEMBL4647217)
Show SMILES Cc1cc(Cl)cc(c1C[C@@H]1CNCCO1)-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12 |r|
Show InChI InChI=1S/C27H28ClN3O3S/c1-14-8-15(28)9-20(19(14)10-16-12-29-6-7-34-16)18-4-5-30-21-11-17(35-24(18)21)13-31-25(32)22-23(26(31)33)27(22,2)3/h4-5,8-9,11,16,22-23,29H,6-7,10,12-13H2,1-3H3/t16-,22?,23?/m1/s1
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MCE
PC cid
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UniChem
Article
PubMed
n/an/an/an/a 25n/an/an/an/a



RAPT Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of USP7 in human RKO cells transfected with p53 luciferase reporter vector assessed as increase in p53-dependent luciferase activity measu...

J Med Chem 63: 5398-5420 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T
More data for this
Ligand-Target Pair