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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 1053   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM1053
PNG
(Hydroxyethylene dipeptide isostere 42 | N-[2(R)-Hy...)
Show SMILES [H][C@@]1(NC(=O)[C@@H](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)Cc2ccc(CCC(OC)OC)cc2)[C@H](O)Cc2ccccc12 |r|
Show InChI InChI=1S/C38H50N2O7/c1-38(2,3)47-37(44)39-31(22-26-11-7-6-8-12-26)32(41)24-29(21-27-17-15-25(16-18-27)19-20-34(45-4)46-5)36(43)40-35-30-14-10-9-13-28(30)23-33(35)42/h6-18,29,31-35,41-42H,19-24H2,1-5H3,(H,39,44)(H,40,43)/t29-,31+,32+,33-,35+/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.0800n/an/an/an/a5.530



Merck Research Laboratories



Assay Description
Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...

J Med Chem 35: 1702-9 (1992)


Article DOI: 10.1021/jm00088a004
BindingDB Entry DOI: 10.7270/Q2N877ZC
More data for this
Ligand-Target Pair