Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM11821 ((3R,4R)-N-(4-{4-[5-(4,4-dimethylpiperidin-1-yl)-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Max-Planck-Institut fuer Biochemie | Assay Description An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide... | J Med Chem 48: 163-70 (2005) Article DOI: 10.1021/jm049701n BindingDB Entry DOI: 10.7270/Q21C1V3S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM11821 ((3R,4R)-N-(4-{4-[5-(4,4-dimethylpiperidin-1-yl)-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | 7.2 | 22 |
Max-Planck-Institut fuer Biochemie | Assay Description In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a... | J Med Chem 48: 163-70 (2005) Article DOI: 10.1021/jm049701n BindingDB Entry DOI: 10.7270/Q21C1V3S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |