Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ephrin type-A receptor 4 [1-949,A922V] (Homo sapiens (Human)) | BDBM11985 (4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Sanford-Burnham Medical Research Institute | Assay Description Protein A-coasted wells (from Pierce Biotechnology) were used to immobilize Eph receptor Fc fusion proteins (from R&D systems)incubated at 1 ug/ml in... | Chem Biol Drug Des 78: 667-78 (2011) Article DOI: 10.1111/j.1747-0285.2011.01199.x BindingDB Entry DOI: 10.7270/Q2FN14QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lethal factor (Bacillus anthracis) | BDBM11985 (4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.50E+3 | -33.5 | 3.80E+3 | n/a | n/a | n/a | n/a | 7.2 | 27 |
Montana State University | Assay Description For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur... | J Med Chem 49: 5232-44 (2006) Article DOI: 10.1021/jm0605132 BindingDB Entry DOI: 10.7270/Q20C4T19 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicative DNA helicase (Staphylococcus aureus) | BDBM11985 (4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Microbiotix, Inc Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay | Bioorg Med Chem 17: 4466-76 (2009) Article DOI: 10.1016/j.bmc.2009.05.014 BindingDB Entry DOI: 10.7270/Q22F7NGH | |||||||||||
More data for this Ligand-Target Pair |