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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 120979   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 8


(Homo sapiens (Human))		BDBM120979
PNG
(US8716285, 36)
Show SMILES CN(C1CCc2ccc(cc2C1)C(=O)NO)c1nccc(n1)-c1cccnc1
Show InChI InChI=1S/C21H21N5O2/c1-26(21-23-10-8-19(24-21)16-3-2-9-22-13-16)18-7-6-14-4-5-15(20(27)25-28)11-17(14)12-18/h2-5,8-11,13,18,28H,6-7,12H2,1H3,(H,25,27)
PDB
MMDB

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KEGG

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PC sid
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Similars
US Patent
n/an/a 3.04E+3n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...

US Patent US8716285 (2014)


BindingDB Entry DOI: 10.7270/Q2K072XG
More data for this
Ligand-Target Pair