BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 135066   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM135066
PNG
(US8846698, 553)
Show SMILES CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc4ccccc4n3)c2)c2cnc(N)nc12
Show InChI InChI=1S/C25H24N8O3/c1-25(2,14-34)33-12-19(18-10-28-24(26)30-23(18)33)22(36)16-7-17(9-27-8-16)29-21(35)13-32-11-15-5-3-4-6-20(15)31-32/h3-12,34H,13-14H2,1-2H3,(H,29,35)(H2,26,28,30)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 4.40n/an/an/an/an/an/a



Pfizer Limited

US Patent


Assay Description
Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...

US Patent US8846698 (2014)


BindingDB Entry DOI: 10.7270/Q2F47MTW
More data for this
Ligand-Target Pair