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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 143316   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM143316
PNG
(US8940893, 1)
Show SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CC2(C1)CN(C2)C(=O)C=C
Show InChI InChI=1S/C26H24N6O2/c1-2-21(33)31-14-26(15-31)12-18(13-26)32-25-22(24(27)28-16-29-25)23(30-32)17-8-10-20(11-9-17)34-19-6-4-3-5-7-19/h2-11,16,18H,1,12-15H2,(H2,27,28,29)
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Similars
US Patent
n/an/a 1n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
An HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...

US Patent US8940893 (2015)


BindingDB Entry DOI: 10.7270/Q2PV6J3P
More data for this
Ligand-Target Pair