BindingDB PrimarySearch

Found 2 hits of ic50 for monomerid = 15318
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112] (Homo sapiens (Human))	BDBM15318 (6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-f...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...				Bioorg Med Chem Lett 13: 3983-7 (2003) Article DOI: 10.1016/j.bmcl.2003.08.056 BindingDB Entry DOI: 10.7270/Q2JD4V11
Merck Research Laboratories					More data for this Ligand-Target Pair				3D Structure (docked)
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112] (Homo sapiens (Human))	BDBM15318 (6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-f...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...				Bioorg Med Chem Lett 13: 3983-7 (2003) Article DOI: 10.1016/j.bmcl.2003.08.056 BindingDB Entry DOI: 10.7270/Q2JD4V11
Merck Research Laboratories					More data for this Ligand-Target Pair