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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 1570   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gag-Pol polyprotein [600-1027,R876K]/[600-1155]


(Human immunodeficiency virus type 1)
BDBM1570
PNG
(2-ethyl-5-(4-hydroxyphenyl)-9-methyl-2,4,9,15-tetr...)
Show SMILES CCN1c2ncccc2C(=O)N(C)c2ccc(nc12)-c1ccc(O)cc1
Show InChI InChI=1S/C20H18N4O2/c1-3-24-18-15(5-4-12-21-18)20(26)23(2)17-11-10-16(22-19(17)24)13-6-8-14(25)9-7-13/h4-12,25H,3H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 38: 4830-8 (1995)


Article DOI: 10.1021/jm00024a010
BindingDB Entry DOI: 10.7270/Q23B5XBJ
More data for this
Ligand-Target Pair
Gag-Pol polyprotein [600-1027,Y780C]/[600-1155,Y780C]


(Human immunodeficiency virus type 1)
BDBM1570
PNG
(2-ethyl-5-(4-hydroxyphenyl)-9-methyl-2,4,9,15-tetr...)
Show SMILES CCN1c2ncccc2C(=O)N(C)c2ccc(nc12)-c1ccc(O)cc1
Show InChI InChI=1S/C20H18N4O2/c1-3-24-18-15(5-4-12-21-18)20(26)23(2)17-11-10-16(22-19(17)24)13-6-8-14(25)9-7-13/h4-12,25H,3H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 38: 4830-8 (1995)


Article DOI: 10.1021/jm00024a010
BindingDB Entry DOI: 10.7270/Q23B5XBJ
More data for this
Ligand-Target Pair