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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 159273   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sortilin


(Homo sapiens (Human))
BDBM159273
PNG
(US10195186, Example 51 | US9682967, 49)
Show SMILES Cc1ccc(NC(=O)c2cc(c(cc2C(O)=O)C(F)(F)F)C(F)(F)F)nc1C
Show InChI InChI=1S/C17H12F6N2O3/c1-7-3-4-13(24-8(7)2)25-14(26)9-5-11(16(18,19)20)12(17(21,22)23)6-10(9)15(27)28/h3-6H,1-2H3,(H,27,28)(H,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 640n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US10195186 (2019)


BindingDB Entry DOI: 10.7270/Q2474CZW
More data for this
Ligand-Target Pair
Sortilin


(Homo sapiens (Human))
BDBM159273
PNG
(US10195186, Example 51 | US9682967, 49)
Show SMILES Cc1ccc(NC(=O)c2cc(c(cc2C(O)=O)C(F)(F)F)C(F)(F)F)nc1C
Show InChI InChI=1S/C17H12F6N2O3/c1-7-3-4-13(24-8(7)2)25-14(26)9-5-11(16(18,19)20)12(17(21,22)23)6-10(9)15(27)28/h3-6H,1-2H3,(H,27,28)(H,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
734n/a 750n/an/an/an/a7.4n/a



H. Lundbeck A/S

US Patent


Assay Description
The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...


US Patent US9682967 (2017)


BindingDB Entry DOI: 10.7270/Q22805SC
More data for this
Ligand-Target Pair