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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 177901   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))
BDBM177901
PNG
(US9120791, Example 134 | US9603854, 134)
Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1C#N
Show InChI InChI=1S/C43H40ClN5O4/c44-32-12-17-36(42(51)48-27-31-9-2-1-7-29(31)23-34(48)28-46-19-21-53-22-20-46)37(24-32)41-25-38(40-11-5-6-18-47(40)41)43(52)49(33-13-15-35(50)16-14-33)39-10-4-3-8-30(39)26-45/h1-4,7-10,12-17,24-25,34,50H,5-6,11,18-23,27-28H2/t34-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 37n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...


US Patent US9603854 (2017)


BindingDB Entry DOI: 10.7270/Q2GX4DMT
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Mus musculus (Mouse))
BDBM177901
PNG
(US9120791, Example 134 | US9603854, 134)
Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1C#N
Show InChI InChI=1S/C43H40ClN5O4/c44-32-12-17-36(42(51)48-27-31-9-2-1-7-29(31)23-34(48)28-46-19-21-53-22-20-46)37(24-32)41-25-38(40-11-5-6-18-47(40)41)43(52)49(33-13-15-35(50)16-14-33)39-10-4-3-8-30(39)26-45/h1-4,7-10,12-17,24-25,34,50H,5-6,11,18-23,27-28H2/t34-/m0/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 37n/an/an/an/a7.4n/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...


US Patent US9120791 (2015)


BindingDB Entry DOI: 10.7270/Q21N7ZWC
More data for this
Ligand-Target Pair