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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 187210   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM187210
PNG
(US9670181, 86 4-((6-ethoxy-2-(ethylamino)-7-fluoro...)
Show SMILES CCCc1nc(O)c(Cc2cc3cc(OCC)c(F)cc3nc2NCC)c2cc(OC)c(OC)cc12
Show InChI InChI=1S/C28H32FN3O4/c1-6-9-22-19-14-26(35-5)25(34-4)13-18(19)20(28(33)32-22)11-17-10-16-12-24(36-8-3)21(29)15-23(16)31-27(17)30-7-2/h10,12-15H,6-9,11H2,1-5H3,(H,30,31)(H,32,33)
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MMDB

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PC cid
PC sid
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US Patent
n/an/a 0.300n/an/an/an/a7.425



ALLERGAN, INC.; EXONHIT THERAPEUTICS SA

US Patent


Assay Description
The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE® from Perkin Elmer). This c...


US Patent US9670181 (2017)


BindingDB Entry DOI: 10.7270/Q21Z42KJ
More data for this
Ligand-Target Pair