Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 211793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM211793 (US9290459, 24.1 | US9475779, E.2 | US9670166, 24.1) Show SMILES CS(=O)(=O)c1cc(ccc1C1N(CCCO)C(=O)N(C2=C1C(=O)CC2)c1cccc(c1)C(F)(F)F)C#N |c:20| Show InChI InChI=1S/C25H22F3N3O5S/c1-37(35,36)21-12-15(14-29)6-7-18(21)23-22-19(8-9-20(22)33)31(24(34)30(23)10-3-11-32)17-5-2-4-16(13-17)25(26,27)28/h2,4-7,12-13,23,32H,3,8-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9290459 (2016) BindingDB Entry DOI: 10.7270/Q2KS6QD5
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM211793 (US9290459, 24.1 | US9475779, E.2 | US9670166, 24.1) Show SMILES CS(=O)(=O)c1cc(ccc1C1N(CCCO)C(=O)N(C2=C1C(=O)CC2)c1cccc(c1)C(F)(F)F)C#N |c:20| Show InChI InChI=1S/C25H22F3N3O5S/c1-37(35,36)21-12-15(14-29)6-7-18(21)23-22-19(8-9-20(22)33)31(24(34)30(23)10-3-11-32)17-5-2-4-16(13-17)25(26,27)28/h2,4-7,12-13,23,32H,3,8-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...				US Patent US9670166 (2017) BindingDB Entry DOI: 10.7270/Q25Q4T8F
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM211793 (US9290459, 24.1 | US9475779, E.2 | US9670166, 24.1) Show SMILES CS(=O)(=O)c1cc(ccc1C1N(CCCO)C(=O)N(C2=C1C(=O)CC2)c1cccc(c1)C(F)(F)F)C#N |c:20| Show InChI InChI=1S/C25H22F3N3O5S/c1-37(35,36)21-12-15(14-29)6-7-18(21)23-22-19(8-9-20(22)33)31(24(34)30(23)10-3-11-32)17-5-2-4-16(13-17)25(26,27)28/h2,4-7,12-13,23,32H,3,8-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...				US Patent US9475779 (2016) BindingDB Entry DOI: 10.7270/Q2QJ7G77
					More data for this Ligand-Target Pair