Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hematopoietic prostaglandin D synthase (Homo sapiens (Human)) | BDBM21615 (1-phenyl-1H-pyrazole-4-carboxylic acid | Pyrazole,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 8.90E+5 | n/a | n/a | n/a | n/a | 7.2 | 22 |
AstraZeneca | Assay Description The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w... | J Med Chem 51: 2178-86 (2008) Article DOI: 10.1021/jm701509k BindingDB Entry DOI: 10.7270/Q2Z036FR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |