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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 226847   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor [441-796]


(Homo sapiens (Human))
BDBM226847
PNG
(US9328096, 540)
Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1
Show InChI InChI=1S/C26H18Cl2FN7O2/c1-14-22(13-31-34-14)32-26(38)21-12-23(36(35-21)15-6-3-2-4-7-15)33-25(37)17-10-16(18(27)11-19(17)28)24-20(29)8-5-9-30-24/h2-13H,1H3,(H,31,34)(H,32,38)(H,33,37)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.51n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair