Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 22778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM22778 (6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...) Show SMILES Clc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl Show InChI InChI=1S/C8H4Cl2N2O2/c9-3-1-5-6(2-4(3)10)12-8(14)7(13)11-5/h1-2H,(H,11,13)(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes				J Med Chem 39: 3248-55 (1996) Article DOI: 10.1021/jm960214k BindingDB Entry DOI: 10.7270/Q2QC02KC
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM22778 (6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...) Show SMILES Clc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl Show InChI InChI=1S/C8H4Cl2N2O2/c9-3-1-5-6(2-4(3)10)12-8(14)7(13)11-5/h1-2H,(H,11,13)(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys Inc. Curated by ChEMBL					Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...				J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM22778 (6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...) Show SMILES Clc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl Show InChI InChI=1S/C8H4Cl2N2O2/c9-3-1-5-6(2-4(3)10)12-8(14)7(13)11-5/h1-2H,(H,11,13)(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity towards strychnine - insensitive glycine site of NMDA receptor in presence of [3H]- Gly				Bioorg Med Chem Lett 1: 751-756 (1991) Article DOI: 10.1016/S0960-894X(01)81062-3 BindingDB Entry DOI: 10.7270/Q2J67GTV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM22778 (6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione | 6...) Show SMILES Clc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl Show InChI InChI=1S/C8H4Cl2N2O2/c9-3-1-5-6(2-4(3)10)12-8(14)7(13)11-5/h1-2H,(H,11,13)(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity towards strychnine - insensitive glycine site of NMDA in presence of [3H]- CPP				Bioorg Med Chem Lett 1: 751-756 (1991) Article DOI: 10.1016/S0960-894X(01)81062-3 BindingDB Entry DOI: 10.7270/Q2J67GTV
					More data for this Ligand-Target Pair