Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 256352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM256352 (US9487490, 3B) Show SMILES OC(=O)[C@H]1CCC(=CC1)c1nn(C(=O)c2c(Cl)cccc2C2CC2)c2cccc(F)c12 |r,c:6| Show InChI InChI=1S/C24H20ClFN2O3/c25-17-4-1-3-16(13-7-8-13)20(17)23(29)28-19-6-2-5-18(26)21(19)22(27-28)14-9-11-15(12-10-14)24(30)31/h1-6,9,13,15H,7-8,10-12H2,(H,30,31)/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	4
Merck Sharp & Dohme Corp. US Patent					Assay Description To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...				US Patent US9487490 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WQN
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