Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 256353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of Nuclear receptor ROR-gamma (RORgT) (Homo sapiens (Human))	BDBM256353 (US9487490, 4A) Show SMILES CC(C)(C)OC(=O)C1CCC(=CC1)c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cc(ccc12)C(=O)N1CC(F)(F)C1 |c:10| Show InChI InChI=1S/C30H27ClF5N3O4/c1-28(2,3)43-27(42)17-9-7-16(8-10-17)24-19-12-11-18(25(40)38-14-29(32,33)15-38)13-22(19)39(37-24)26(41)23-20(30(34,35)36)5-4-6-21(23)31/h4-7,11-13,17H,8-10,14-15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	4
Merck Sharp & Dohme Corp. US Patent					Assay Description To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...				US Patent US9487490 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WQN
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