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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 264269   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Wee1-like protein kinase


(Homo sapiens (Human))		BDBM264269
PNG
(6-(2,6-Dichlorophenyl)-2-((4-(piperazin-1-yl)pheny...)
Show SMILES Clc1cccc(Cl)c1-n1cc(-c2cccnc2)c2nc(Nc3ccc(cc3)N3CCNCC3)ncc2c1=O |(5.33,5,;6.67,4.23,;8,5,;9.34,4.23,;9.34,2.69,;8,1.93,;8,.38,;6.67,2.69,;5.33,1.93,;5.33,.38,;4,-.38,;4,-1.93,;2.67,-2.69,;2.67,-4.23,;4,-5,;5.33,-4.23,;5.33,-2.69,;2.67,.38,;1.33,-.38,;,.38,;-1.33,-.38,;-2.67,.38,;-4,-.38,;-5.33,.38,;-5.33,1.93,;-4,2.69,;-2.67,1.93,;-6.67,2.69,;-8,1.93,;-9.34,2.69,;-9.34,4.23,;-8,5,;-6.67,4.23,;,1.93,;1.33,2.69,;2.67,1.93,;4,2.69,;4,4.23,)|
Show InChI InChI=1S/C28H23Cl2N7O/c29-23-4-1-5-24(30)26(23)37-17-22(18-3-2-10-32-15-18)25-21(27(37)38)16-33-28(35-25)34-19-6-8-20(9-7-19)36-13-11-31-12-14-36/h1-10,15-17,31H,11-14H2,(H,33,34,35)
PDB
MMDB

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US Patent
n/an/a<10n/an/an/an/an/a25



ALMAC DISCOVERY LIMITED

US Patent


Assay Description
In the measurement of Wee-1 activity, a commercial peptide Poly(Lys Tyr(4:1)) hydrobromide was purchased from Sigma Aldrich and used as the substrate...

US Patent US9714244 (2017)


BindingDB Entry DOI: 10.7270/Q2GH9KZ4
More data for this
Ligand-Target Pair