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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM268059 (2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo... | US Patent US9549932 (2017) BindingDB Entry DOI: 10.7270/Q27S7QSC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM268059 (2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474FQK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM268059 (2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo... | US Patent US10772893 (2020) BindingDB Entry DOI: 10.7270/Q2T43X50 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
