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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 276363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))
BDBM276363
PNG
(2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]me...)
Show SMILES CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C(F)F)nn1
Show InChI InChI=1S/C16H13F4N5O/c1-16(19,20)11-3-2-4-13(5-11)25-8-12(23-24-25)9-26-15-21-6-10(7-22-15)14(17)18/h2-8,14H,9H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Lund University



Assay Description
NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...


Bioorg Med Chem 14: 1215-20 (2006)


BindingDB Entry DOI: 10.7270/Q23R0W6K
More data for this
Ligand-Target Pair
Retinoic acid receptor RXR-alpha


(Homo sapiens (Human))
BDBM276363
PNG
(2-[[1-[3-(1,1-Difluoroethyl)phenyl]triazol-4-yl]me...)
Show SMILES CC(F)(F)c1cccc(c1)-n1cc(COc2ncc(cn2)C(F)F)nn1
Show InChI InChI=1S/C16H13F4N5O/c1-16(19,20)11-3-2-4-13(5-11)25-8-12(23-24-25)9-26-15-21-6-10(7-22-15)14(17)18/h2-8,14H,9H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.425



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...


US Patent US10071988 (2018)


BindingDB Entry DOI: 10.7270/Q20Z7591
More data for this
Ligand-Target Pair