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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 292573   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292573
PNG
((S)-N-(2-(diethylamino)propyl)-2-((2-hydroxyethyl)...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCO)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r|
Show InChI InChI=1S/C25H31N7O2S/c1-4-31(5-2)17(3)15-27-25(34)18-13-21(29-23(14-18)26-9-11-33)19-16-28-32-10-8-20(30-24(19)32)22-7-6-12-35-22/h6-8,10,12-14,16-17,33H,4-5,9,11,15H2,1-3H3,(H,26,29)(H,27,34)/t17-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.100n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human full length His-tagged CaMK2delta expressed in baculovirus using Biotin labelled STK1 as substrate after 1 hr in pres...


Citation and Details

Article DOI: 10.1016/j.bmcl.2017.10.040
BindingDB Entry DOI: 10.7270/Q2930WR2
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292573
PNG
((S)-N-(2-(diethylamino)propyl)-2-((2-hydroxyethyl)...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCO)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r|
Show InChI InChI=1S/C25H31N7O2S/c1-4-31(5-2)17(3)15-27-25(34)18-13-21(29-23(14-18)26-9-11-33)19-16-28-32-10-8-20(30-24(19)32)22-7-6-12-35-22/h6-8,10,12-14,16-17,33H,4-5,9,11,15H2,1-3H3,(H,26,29)(H,27,34)/t17-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair