Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C beta type (Rattus norvegicus (rat)) | BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Tumor Biology Center | Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi... | Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myosin light chain kinase, smooth muscle (Homo sapiens (Human)) | BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Tumor Biology Center | Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard | Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken)) | BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Tumor Biology Center | Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain. | Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine)) | BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Tumor Biology Center | Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone. | Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent protein kinase 1 (Bos taurus (bovine)) | BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tumor Biology Center | Assay Description The activity of cGPK, activated by cGMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone. | Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 2 (Mus musculus (mouse)) | BDBM3045 (3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tumor Biology Center | Assay Description The activity of TPK is measured by its ability to transfer 32P from [gamma-32P]ATP to Poly(Glu,Tyr; 4:l)(sigma). | Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C | |||||||||||
More data for this Ligand-Target Pair |