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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 333571   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))		BDBM333571
PNG
(1-(3-tert- butylphenyl)- 3-(3-(6,7- dimethoxy- qui...)
Show SMILES COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cccc(c4)C(C)(C)C)c3)c2cc1OC
Show InChI InChI=1S/C27H28N4O4/c1-27(2,3)17-8-6-9-18(12-17)30-26(32)31-19-10-7-11-20(13-19)35-25-21-14-23(33-4)24(34-5)15-22(21)28-16-29-25/h6-16H,1-5H3,(H2,30,31,32)
PDB
MMDB

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PC cid
PC sid
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Article
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n/an/a 333n/an/an/an/an/an/a



Ambit Biosciences Corporation

Curated by ChEMBL


Assay Description
Inhibition of BRAF V600E mutant-dependent MEK phosphorylation in A375 cells

Bioorg Med Chem Lett 21: 5342-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.019
BindingDB Entry DOI: 10.7270/Q24T6N6Z
More data for this
Ligand-Target Pair