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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 341341   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))		BDBM341341
PNG
(6-chloro-5-(2-(5-(4-chloro-2-fluorophenyl)-2-methy...)
Show SMILES Cc1nn2c3C(N(CCc3nc2s1)C(=O)COc1ccc(nc1Cl)C(N)=O)c1ccc(Cl)cc1F
Show InChI InChI=1S/C22H17Cl2FN6O3S/c1-10-29-31-19-14(28-22(31)35-10)6-7-30(18(19)12-3-2-11(23)8-13(12)25)17(32)9-34-16-5-4-15(21(26)33)27-20(16)24/h2-5,8,18H,6-7,9H2,1H3,(H2,26,33)
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US Patent
n/an/a 5n/an/an/an/an/an/a



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...

US Patent US9765092 (2017)


BindingDB Entry DOI: 10.7270/Q21N838B
More data for this
Ligand-Target Pair