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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 34536   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))
BDBM34536
PNG
(US8546434, 10)
Show SMILES COC(C)(C)[C@@H](N(C[C@@H]1CNC[C@@H]1F)C(=O)[C@@H]1CCCO1)c1nc(nn1Cc1cccc(F)c1)-c1cc(F)ccc1F |r|
Show InChI InChI=1S/C15H23N5O4S/c1-18-12-11(13(21)17-14(18)22)20(5-7-23-2)15(16-12)25-10-6-19-3-8-24-9-4-19/h3-10H2,1-2H3,(H,17,21,22)
PDB
MMDB

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Similars

US Patent
n/an/a 0.900n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
In vitro activity assay using KSP.


US Patent US8546434 (2013)


BindingDB Entry DOI: 10.7270/Q25D8QG9
More data for this
Ligand-Target Pair