Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 35579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM35579 (pyrazolo pyrimidine, 6) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCNCC3)c2n1 Show InChI InChI=1S/C22H28N8O2/c1-23-22(31)26-16-4-2-15(3-5-16)19-27-20(29-10-12-32-13-11-29)18-14-25-30(21(18)28-19)17-6-8-24-9-7-17/h2-5,14,17,24H,6-13H2,1H3,(H2,23,26,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	23
Wyeth Research					Assay Description The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...				J Med Chem 52: 5013-6 (2009) Article DOI: 10.1021/jm900851f BindingDB Entry DOI: 10.7270/Q2SJ1HZD
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM35579 (pyrazolo pyrimidine, 6) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCNCC3)c2n1 Show InChI InChI=1S/C22H28N8O2/c1-23-22(31)26-16-4-2-15(3-5-16)19-27-20(29-10-12-32-13-11-29)18-14-25-30(21(18)28-19)17-6-8-24-9-7-17/h2-5,14,17,24H,6-13H2,1H3,(H2,23,26,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	25
Wyeth Research					Assay Description Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.				J Med Chem 52: 5013-6 (2009) Article DOI: 10.1021/jm900851f BindingDB Entry DOI: 10.7270/Q2SJ1HZD
					More data for this Ligand-Target Pair