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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 355896   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824]


(Homo sapiens (Human))
BDBM355896
PNG
(1-(3-chloro-4-(2H- 1,2,3-triazol-2- yl)phenyl)-3-(...)
Show SMILES CC(C)c1c(NC(=O)Nc2ccc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12
Show InChI InChI=1S/C18H16Cl2N8O/c1-10(2)17-13(9-21-16-8-15(20)26-27(16)17)25-18(29)24-11-3-4-14(12(19)7-11)28-22-5-6-23-28/h3-10H,1-2H3,(H2,24,25,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.00300n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...


US Patent US10442808 (2019)


BindingDB Entry DOI: 10.7270/Q2S75JQ3
More data for this
Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))
BDBM355896
PNG
(1-(3-chloro-4-(2H- 1,2,3-triazol-2- yl)phenyl)-3-(...)
Show SMILES CC(C)c1c(NC(=O)Nc2ccc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12
Show InChI InChI=1S/C18H16Cl2N8O/c1-10(2)17-13(9-21-16-8-15(20)26-27(16)17)25-18(29)24-11-3-4-14(12(19)7-11)28-22-5-6-23-28/h3-10H,1-2H3,(H2,24,25,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.00300n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...


US Patent US9815842 (2017)


BindingDB Entry DOI: 10.7270/Q24F1T0N
More data for this
Ligand-Target Pair