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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 4132   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM4132
PNG
((2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-4-(3,5-di...)
Show SMILES Cc1c(O)cccc1C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)C(=O)N1C[C@@H](Cl)C[C@H]1C(=O)NC(C)(C)C |r|
Show InChI InChI=1S/C27H32ClF2N3O5/c1-14-19(6-5-7-22(14)34)24(36)31-20(10-15-8-17(29)12-18(30)9-15)23(35)26(38)33-13-16(28)11-21(33)25(37)32-27(2,3)4/h5-9,12,16,20-21,23,34-35H,10-11,13H2,1-4H3,(H,31,36)(H,32,37)/t16-,20-,21-,23-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 0.800n/an/an/an/an/an/a



Sankyo Co. Ltd.



Assay Description
The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...

Bioorg Med Chem 7: 2063-72 (1999)


Article DOI: 10.1016/s0968-0896(99)00127-3
BindingDB Entry DOI: 10.7270/Q23T9FD0
More data for this
Ligand-Target Pair